| Objective To investigate the related risk factors of toe amputations in the patients with diabetic foot.Methods A total of 206 patients with DF who were hospitalized in the Department of Endocrinology of Fuyang People's Hospital from October 2013 to May 2016 were divided into non-truncated group (99 cases) and truncated toe group (107 cases).The general informations(age,gender,occupation,diabetes course,diabetic foot course,cardiovascular history,BMI,SBP,DBP,degree of dorsal artery occlusion and Wanger classification) and biochemical characteristics (FBG,HbA1c,TC,TG,LDL-C,HDL-C,hs-CRP,TBIL and WBCC)of each group were collected and analyzed.The related factors of DF toewere assessed by Logistic analysis.Results Compared to non-amputation group, the age, duration of diabetes mellitus, course of diabetic foot, SBP, FBG, HbA1c, TC, LDL-C, hs-CRP, TBIL, white blood cell(WBC) count, degree of dorsal artery occlusion and Wanger classification were all higher than those of non-truncated group, and the prevalence of cardiovascular and cerebrovascular diseases was also significantly different (P<0.05),while BMI, DBP, TG, HDL-C, sex and occupation were similar (P>0.05). Logistic regression analysis showed that the course of diabetes mellitus (P=0.022),TC (P=0.042), LDL-C (P=0.002), hs-CRP (P=0.002), WBCC (P=0.000) and Wanger classification (P=0.000) were related risk factors of amputation. TBIL (P=0.000) was a protective factor.Conclusion The course of diabetes mellitus,TC,LDL-C,hs-CR, the count of WBC and Wanger classification are the risk factors of amputation, and TBIL may be one of the protective effects of amputations. |
