| Objective To investigate the effect of interventional closure surgery on cardiac structure and hemodynamics in children with left-to-right shunt congenital heart disease(CHD). Methods A retrospective analysis was performed on the clinical data of 75 children with CHD who underwent interventional closure surgery in the Second Hospital of Anhui Medical University from June 2011 to June 2016, including 24 cases of atrial septal defect(ASD), 24 cases of ventricular septal defect(VSD), 27 cases of patent ductus arteriosus(PDA).Transthoracic echocardiography was used to detect cardiac structure and changes of hemodynamicrelated indicatorspreoperative,3 daysafter operation, 1 monthafter operation, 3 monthsafter operation, 6 monthsafter operation, and 1 year after operation.Results Compared with preoperativeindicators, after interventional closure surgery, the right ventricular internal diameter(RV), left atrial diameter(LA), left ventricular internal diameter(LV), pulmonary artery pressure(PAP), pulmonary valve flow velocity(PV), mitral valve orifice early diastolic blood flow velocity(MVE), mitral valve dilatation of late maximum blood flow velocity(MVA) decreasedin children with VSD, RV, PAP in children with ASD, tricuspid ostial diastolic early maximum blood flow velocity(TVE), tricuspid regurgitation late maximum blood flow velocity(TVA), PV, and LA, LV, MVE, MVA, AV, and PAP in children with PDA also decreased(P<0.05). The levels of TVE, TVA and PV in children with TV, LV, MVE, MVA, AV and PDA in children with VSD were significantly higher than those before operation(P<0.05).Conclusion Interventional closure surgery can significantly improve the heart structure and hemodynamics in children with left-to-right shunt congenital heart disease, which is an effective treatment and worthclinical promotion. |
