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| 3.0T磁共振扩散加权成像对老年前列腺癌与前列腺增生的鉴别诊断价值 |
| Value of diffusion-weighted 3.0T imaging in differential diagnosis of prostate cancer and benign prostatic hyperplasia in elderly patients |
| 投稿时间：2018-07-26 |
| DOI：10.3969/j.issn.1000-0399.2019.05.005 |
| 中文关键词: 3.0T磁共振扩散加权成像 诊断 老年 前列腺癌 前列腺增生 |
| 英文关键词: 3.0T MR diffusion weighted imaging Diagnosis Elderly Prostate cancer Prostatic hyperplasia |
| 基金项目:南通市科技计划项目（项目编号：HS149113） |
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| 中文摘要: |
| 目的 探究3.0T磁共振扩散加权成像在鉴别诊断老年前列腺癌与老年前列腺增生的应用价值。方法 回顾性分析2016年11月至2017年11月如皋市人民医院收治的136例老年前列腺癌及前列腺增生患者的临床资料，根据病理诊断结果将其中病理确诊的68例老年前列腺癌患者设为观察组，将68例老年前列腺增生患者设为对照组。所有患者均行3.0T磁共振扩散加权成像。比较两组患者表观扩散系数（ADC值）、弥散加权成像（DWI）信号强度及增强磁共振成像（DCE-MRI）参数。结果 观察组患者ADC值低于对照组，差异有统计学意义（P<0.05）；在扩散敏感因子（b）值=50 s/mm2及800 s/mm2时，观察组的DWI信号强度均低于对照组，差异有统计学意义（P<0.05）；观察组DCE-MRI参数（Kep、K trans及Ve）水平均高于对照组，差异有统计学意义（P<0.05）。结论 3.0T磁共振扩散加权成像能够通过ADC值、DWI信号强度及DCE-MRI参数为鉴别诊断老年前列腺癌与前列腺增生提供参考。 |
| 英文摘要: |
| Objective To explore the value of diffusion-weighted 3.0T imaging in differential diagnosis of prostate cancer and benign prostatic hyperplasia in the elderly.Methods The clinical data of 136 elderly patients with prostate cancer and benign prostatic hyperplasia admitted to Rugao People's Hospital of Nantong City from November 2016 to November 2017 were retrospectively analyzed. Sixty-eight patients with pathological diagnosis and elderly patients with prostate cancer were included in observation group, while another 68 elderly patients with benign prostatic hyperplasia as the control group. All patients underwent 3.0T magnetic resonance diffusion-weighted imaging. The apparent diffusion coefficient (ADC value), diffusion-weighted imaging (DWI) signal intensity, and enhanced magnetic resonance imaging (DCE-MRI) parameters were compared between the two groups.Results The ADC value of observation group was lower than that of control group, and the difference was statistically significant (P<0.05); when the diffusion sensitivity factor (b)=50 s/mm2 and 800 s/mm2, the DWI signal intensity of observation group was lower than that of control group, and the difference was statistically significant (P<0.05); DCE-MRI parameters (Kep, K trans and Ve) and levels of observation group were higher than those of control group, and the difference was statistically significant (P<0.05).Conclusion 3.0T MR diffusion-weighted imaging can provide a basis for differential diagnosis of prostate cancer and benign prostatic hyperplasia by ADC value, DWI signal intensity and DCE-MRI parameters. |
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