| Objective To investigate the value of Narrowband imaging (NBI) in Endoscopic submucosal dissection (ESD) for gastric mucosal high-grade intraepithelial neoplasia. Methods A total of221 patients with gastric mucosal HGIN admitted to Henan Armed Police Corps Hospital from Octo 2011 to Sept 2017 were selected.According to the different ways of preoperative examination, 113 patients were divided into NBI group and 98 patients in WLE group. Both groups received ESD treatment,thenthe clarity of preoperative endoscopic images, the general situation of operation, perioperative complications,recurrence and survival during the follow-upwere compared. Results ompared with WLE, the image clarity score of NBI was significantly higher for the mucosal microvascular morphology and pathological contour (P<0.01), but there was no statistical significance in image quality of gastric small concave between two kinds of endoscopy (P>0.05).In WLE group, the operation time was (72.14±19.86) min, the diameter of the lesion was (3.81±1.09) cm, the one-time resection rate was 90.82%, and the cure resection rate was 84.69%, while those in NBI groupwas (52.37±20.23) min,(5.87±2.14) cm, 100.00%, and 93.81%,respectively, and the difference was statistically significant(P<0.05). In NBI group, the operative time was shorter, the diameter of lesions was larger, and the one-time excision rate and curative resection rate werehigher, and the difference was statistically significant(P<0.05).During the follow-up after surgery, the recurrence rate of NBIgroup was 0.88% andthe incidence of surgical complications was 5.31%, both of which were lower than those of WLE group(11.22%, 25.51%), and the difference was statisticallysignificant(P<0.05).Conclusion NBI combined with ESD in the surgical treatment of gastric mucosa HGIN can achieve accurate markers and circumferential dissection of the lesion area based on clearer endoscopic images, and thereby significantly shorten the operation time and improve the efficacy and safety of the lesion resection. |
