| Objective To explore the influence of three blood transfusion methods on perioperative immune function of high-risk parturient. Methods The clinical data of 120 high-risk parturients admitted to Gaoming District People's Hospital of Foshan City from February 2018 to March 2020 were retrospectively analyzed. According to different blood transfusion methods, 120 high-risk parturients were divided into autologous group, mixed group (both autologous and allogeneic blood transfusion) and allogeneic group, with 40 cases in each group. The general conditions of the three groups of patients and the differences of peripheral blood T cell subsets, immunoglobulin and complement C3 levels before and after surgery were compared. Results The difference of CD4+/CD8+ before and after operation was (0.18±0.08) in autologous group, (0.43±0.16) in mixed group and (0.78±0.28) in allogeneic group, with statistical significance (P<0.05). The level difference of immunoglobulin G before and after operation was (0.42±0.13) g/L in autologous group, (3.52±0.96) g/L in mixed group and (6.14±1.78) g/L in allogeneic group, with statistical significance (P<0.05). The level difference of immunoglobulin A before and after operation was (0.17±0.08) g/L in autologous group, (1.02±0.28) g/L in mixed group and (1.32±0.30) g/L in allogeneic group, with statistical significance (P<0.05). The difference of C3 level before and after operation was (0.49±0.23) g/L in autologous group, (0.22±0.14) g/L in mixed group and (0.04±0.02) g/L in allogeneic group, with statistical significance (P<0.05). Conclusion Among the three blood transfusion methods, autologous blood transfusion has the least influence on perioperative immune function of high-risk parturients, so it is recommended to adopt this blood transfusion method clinically. |
