| Objective To explore the application value of musculoskeletal ultrasound in acute attack stage of gouty arthritis and its correlation with blood index. Methods From January to December 2019, 50 elderly patients who received a physical examination at the Third People's Hospital of Yancheng City, Jiangsu Province were selected as the healthy control group, and 107 elderly patients with gouty arthritis admitted to this hospital during the same period were selected as the observation group. The case observation group was divided into acute attack group(44 cases) and stable stage group(63 cases) according to clinical symptoms and history inquiry results. All patients underwent joint musculoskeletal ultrasound examination and disease-related blood index examination, and the correlation between musculoskeletal ultrasound score and disease-related blood index was analyzed. Results There were statistically significant differences in the comprehensive musculoskeletal ultrasound scores of the healthy control group, stable group and acute attack group(P<0.05).The AUC for the differential diagnosis of gouty arthritis was 0.885, and the accuracy, sensitivity, and specificity was 71.44%, 77.25%, and 73.61% (P<0.001), respectively, with a differential threshold of 4.38 points for the comprehensive score of musculoskeletal ultrasound. The AUC for the differential diagnosis of stable gouty arthritis versus acute exacerbation was 0.861, and the accuracy, sensitivity, and specificity was 70.81%, 76.36%, and 71.49% (P<0.001), respectively, with a differential threshold of 8.89 points for the comprehensive score of musculoskeletal ultrasound. The musculoskeletal ultrasound imaging score was 8.89 points. The comprehensive score of musculoskeletal ultrasound of patients with acute onset gouty arthritis was positively correlated with 5-HT, SP, IL-6, TNF-α, and hs-CRP(P<0.05). Conclusions The comprehensive score of musculoskeletal ultrasound is correlated with blood indicators related to the disease. Musculoskeletal ultrasound has certain clinical value in distinguishing the acute onset of gouty arthritis from the stable phase. |
