| Objective To investigate the diagnostic value of shear wave elastography in quantitative analysis of peripheral stiffness of breast lesions. Methods The clinical data of 60 patients diagnosed in the South District of the First Affiliated Hospital of University of Science and Technology of China from December 2018 to may 2020 were retrospectively analyzed, including 60 lesions, 31 benign lesions and 29 malignant lesions. The elastic modulus of the lesions (Emax, Emin, Emean, and Esd) and the surrounding area (shell 1.0, 2.0, and 3.0 mm) were measured and recorded, and the performance of "hard ring sign" was compared. The elastic modulus values of benign and malignant lesions and surrounding tissues were compared. The receiver operating characteristic (ROC) curve was drawn and the area under the curve (AUC) of each modulus of elasticity was compared to obtain the modulus of elasticity with the greatest diagnostic value. Lastly, the diagnostic value of BI-RADS classification, elastography and their combination were compared. Results The age of benign group was younger than that of malignant group, and the difference was statistically significant (P<0.05). There was no significant difference in the maximum diameter of lesions between benign and malignant groups (P>0.05). The incidence of "hard ring sign" in malignant group was higher than that in benign group (P<0.05). There was no significant difference in the elastic modulus of Emin between benign and malignant groups (P> 0.05); the elastic modulus of Emean, Emax and Esd in malignant group were higher than those in benign group (P<0.05). ROC of elastic modulus (Emean, Emax, Esd) showed that AUC of shell 2.0 mm Emax was the largest, which was 0.843, cut-off value was 97.06kPa, sensitivity was 82.76%, specificity was 74.19%. The AUC value was 0.965, the sensitivity was 93.1%, and the specificity was 93.5%. Conclusions The combination of conventional ultrasound BI-RADS classification and shear wave ultrasound elastography can significantly improve the diagnostic accuracy of benign and malignant breast lesions. |
