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| 赤藓糖醇龈下喷砂辅助龈下刮治及根面平整术治疗中重度慢性牙周炎的临床疗效 |
| Subgingival erythritol powder air-polishing as an additional approach to scaling and root planning in treatment with untreated moderate to severe chronic periodontitis |
| 投稿时间：2021-02-16 |
| DOI：10.3969/j.issn.1000-0399.2021.07.006 |
| 中文关键词: 牙周炎 龈下喷砂 赤藓糖醇 |
| 英文关键词: Periodontitis Subgingival air-polishing Erythritol |
| 基金项目:安徽医科大学校科研基金（项目编号：2018xkj023） |
| 作者 | 单位 | | 程楠 | 230032 合肥 安徽医科大学口腔医学院, 安徽医科大学附属口腔医院, 安徽省口腔疾病研究中心实验室 | | 孙晓瑜 | 230032 合肥 安徽医科大学口腔医学院, 安徽医科大学附属口腔医院, 安徽省口腔疾病研究中心实验室 | | 王晓玮 | 230032 合肥 安徽医科大学口腔医学院, 安徽医科大学附属口腔医院, 安徽省口腔疾病研究中心实验室 | | 张雷 | 230032 合肥 安徽医科大学口腔医学院, 安徽医科大学附属口腔医院, 安徽省口腔疾病研究中心实验室 | | 洪彪 | 230032 合肥 安徽医科大学口腔医学院, 安徽医科大学附属口腔医院, 安徽省口腔疾病研究中心实验室 | | 汪洋 | 230032 合肥 安徽医科大学口腔医学院, 安徽医科大学附属口腔医院, 安徽省口腔疾病研究中心实验室 |
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| 中文摘要: |
| 目的 探讨赤藓糖醇龈下喷砂辅助龈下刮治及根面平整术治疗中重度慢性牙周炎的临床疗效。方法 选择2020年6月至2020年12月就诊于安徽医科大学附属口腔医院牙周黏膜科的中度或重度慢性牙周炎患者29例，患者龈上洁治术后1周行牙周专科检查，以专科检查的各项数据作为基线数据，采用半口对照随机分组的设计原则，随机选择患者一侧牙为试验组，行赤藓糖醇龈下喷砂+龈下刮治及根面平整术治疗；另一侧为对照组，仅行龈下刮治及根面平整术。选取病变程度相似，至少有一个位点牙周探诊深度≥6 mm且探诊后出血的1~3对牙取龈下菌斑和龈沟液，试验组和对照组共纳入43对患牙，每组43颗患牙。通过苯甲酰精氨酸萘酰胺试验（BANA试验）检测基线（T0）、术后1周（T1）和术后1个月（T2）牙周袋内红色复合体的变化。1个月后复查各组探诊深度、探诊后出血和出血指数等临床指标，评价治疗效果。结果 T0时，试验组与对照组各项临床指标及细菌学指标差异无统计学意义（P>0.05）。不同时间点菌斑和龈沟液中BANA值比较，差异有统计学意义（P<0.05），而两组之间比较，差异无统计学意义，且时间和组间不存在交互作用（P>0.05）。组内比较，T2时，对照组龈下菌斑中BANA值多于T1时，差异有统计学意义（P<0.05），而试验组无变化，差异无统计学意义（P>0.05）。两组T2时牙周探诊深度、探诊后出血百分比和出血指数均较T0降低，其中，试验组牙周探诊深度改善程度（1.29±0.84） mm优于对照组（0.95±0.93） mm，差异有统计学意义（P<0.05），余组间差异无统计学意义（P>0.05）。结论 赤藓糖醇龈下喷砂作为龈下刮治及根面平整术的辅助治疗能提高慢性牙周炎的临床疗效，抑制菌斑中红色复合体细菌的聚集。 |
| 英文摘要: |
| Objective To investigate the effect of subgingival erythritol air-polishing as an additional approach to scaling and root planning in treating subjects with moderate to severe chronic periodontitis. Methods Twenty-nine patients with moderate to severe chronic periodontitis were recruited. Two quadrants in each subject were randomly assigned, according to a split-mouth design, to receive scaling and root planing (SRP) and subgingival erythritol air-polishing (Test group) or SRP (Control group). A total of 43 pairs of teeth, at least one site with probing depth ≥ 6 mm and bleeding on probing were chosen to collect plaque and gingival crevicular fluid. Clinical parameters, such as probing depth, bleeding on probing and bleeding index were measured at baseline, and one month after the treatment. The volumes of red complex in subgingival dental plaque and gingival crevicular fluid were measured at baseline(T0) and seven days (T1), and one month (T2) after the treatments using BANA test. Results At baseline, no statistically significant differences in clinical parameters and the volumes of red complex in subgingival dental plaque and gingival crevicular fluid were found between the Test and Control groups.The difference of BANA values in plaque and gingival creval fluid at different time points was statistically significant (P<0.05), while the difference between the two groups was not statistically significant, and there was no interaction between time and groups (P>0.05). The volumes of red complex in subgingival dental plaque and gingival crevicular fluid gingival crevicular fluid kept lower for seven days to one month, except the volumes of red complex in subgingival dental plaque in control groups,which showed a significant increase one month after SRP. Notably, the test group showed greater reduction in probing depth[(1.29±0.84)mm] than that in the control group[(0.95±0.93)mm] at one month (P<0.05). Conclusion It suggests that subgingival erythritol air-polishing, as an additional approach to scaling and root planning in treating subjects with moderate to severe chronic periodontitis, may be beneficial for periodontal health and the reduction of the total volume of the red complex in subgingival dental biofilm. |
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