| Objective To explore the evaluation value of quick sequential organ failure assessment (qSOFA) score combined with serum interleukin-6 (IL-6), procalcitonin (PCT) and C-reactive protein (CRP) levels for prognosis of ICU patients with septic shock. Methods Ninety-three ICU patients with septic shock in Hefei Third People's Hospital from May 2018 to March 2021 were enrolled as the research objects. According to presence or absence of multiple organ dysfunction syndrome (MODS), they were divided into mild group and severe group, and were divided into survival group and death group according to 28 day survival. The qSOFA score, levels of serum IL-6, PCT and CRP were compared between these two groups. Receiver operating characteristic (ROC) curve was used to analyze the value of qSOFA score combined with serum IL-6, PCT and CRP levels in evaluating the severity and prognosis of ICU patients with septic shock. Results ①The qSOFA score, levels of serum IL-6, PCT and CRP in severe group were higher than those in mild group (P<0.05), and AUC of qSOFA score combined with serum IL-6, PCT and CRP (0.826) in evaluating the severity of septic shock was greater than that of single qSOFA score (0.652), serum IL-6 (0.765), PCT (0.703) and CRP (0.665) (P<0.05); ②The qSOFA score, levels of serum IL-6, PCT and CRP in death group were higher than those in survival group (P<0.05), and AUC of qSOFA score combined with serum IL-6, PCT and CRP (0.882) in evaluating the prognosis of septic shock was higher than that of qSOFA score alone (0.733), serum IL-6 (0.612), PCT (0.690) and CRP (0.747) (P<0.05). Conclusions The qSOFA score combined with serum IL-6, PCT and CRP levels has a certain reference value for the severity and prognosis assessment of ICU patients with septic shock. |
