文章摘要
肺癌化疗患者灵性健康与希望水平社会支持及免疫功能的相关性
Correlation between spiritual health hope level social support andimmune function in patients with lung cancer undergoing chemotherapy
投稿时间:2021-04-10  
DOI:10.3969/j.issn.1000-0399.2022.01.022
中文关键词: 肺癌  灵性健康  希望水平  社会支持  免疫功能
英文关键词: Lung cancer  Spiritual health  Hope level  Social support  Immune function
基金项目:南通市科技局2018民生科技面上项目(项目编号:MS12018026)
作者单位
钱爱云 226000 江苏南通 南通市第六人民医院呼吸科 
徐费凡 226000 江苏南通 南通市第六人民医院检验科 
樊伟 226000 江苏南通 南通市第六人民医院呼吸科 
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中文摘要:
      目的 调查原发性肺癌(肺癌)化疗患者灵性健康现况,探讨其与希望水平、社会支持及免疫功能的相关性。方法 采用方便抽样选取2019年12月至2020年9月南通市第六人民医院住院化疗的肺癌患者110例,采用一般资料调查表、中文版慢性疾病治疗功能评估-灵性量表、中文版希望量表、社会支持评定量表进行横断面调查调查,检测静脉血标本T细胞亚群、白介素-2水平。结果 110例肺癌化疗患者灵性健康总分为(33.07±10.26)分,灵性健康与希望水平[(39.16±5.21)分]呈正相关(r=0.741,P<0.001),与社会支持[(31.89±7.51)分]呈正相关(r=0.232,P=0.046),与CD4+T细胞(r=0.427,P=0.018)、白介素-2(IL-2)呈正相关(r=0.403,P<0.001),不同化疗次数、生活状况的肺癌化疗患者T淋巴细胞、IL-2差异有统计学意义(P<0.05)。结论 肺癌化疗患者灵性健康处于中等水平,在临床实践中可提高患者的希望水平,给予多维的社会支持来提升患者的灵性健康,增强免疫功能,提高抗病能力。
英文摘要:
      Objective To investigate the spiritual health status of patients with lung cancer undergoing chemotherapy in China and its correlation with hope level, social support and immune function.Methods A cross-sectional study was conducted among 110 lung cancer patients who were hospitalized for chemotherapy in Nantong Sixth People's Hospital from December 2019 to September 2020 by convenient sampling. General information questionnaire, Chinese version of chronic disease treatment function assessment spirituality scale, Chinese version of hope scale, and social support rating scale were used to investigate. The number of immune cells in venous blood samples were collected and detected.Results In 110 patients with lung cancer chemotherapy, the total score of spiritual health was(33.07±10.26). Spiritual health was positively correlated with level of hope(39.16±5.21, r=0.741, P<0.001), social support(31.89±7.51, r=0.232, P=0.046), CD4+T cell percentage(r=0.427, P=0.018) and IL-2 concentration(r=0.403, P<0.001). T cell percentage and IL-2 concentration were different in patients with different times of chemotherapy and different living conditions, and the difference was statistically significant (P<0.05).Conclusions Spiritual health of lung cancer patients with chemotherapy is at a medium level. In clinical practice, by improving patients' hope level and giving high-level and multi-dimensional social support, we can improve patients' spiritual health, enhance immune function and improve disease resistance.
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