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| 正念疗法对多发性硬化症患者疲劳及负性情绪影响的Meta分析 |
| Meta-analysis of effects of mindfulness therapy on fatigue symptoms and negative emotions in patients with multiple sclerosis |
| 投稿时间：2021-11-16 |
| DOI：10.3969/j.issn.1000-0399.2022.05.019 |
| 中文关键词: 正念疗法 多发性硬化症 疲劳 情绪,负性 Meta分析 |
| 英文关键词: Mindfulness therapy Multiple sclerosis Fatigue Negative emotions Meta analysis |
| 基金项目:2020年南京市卫健委卫生科技重点发展项目(项目编号:ZKX20012),江苏省医院协会医院管理研究中心创新研究课题项目(项目编号:JSYGY-3-2021-190) |
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| 中文摘要: |
| 目的 评价正念疗法对多发性硬化症患者疲劳症状和负性情绪的干预效果。方法 计算机检索中国知网、万方、维普、中国生物医学文献服务系统、PubMed、Cochrane Library、Web of science、EMbase、CINHL等建库至2021年8月12日中有关正念疗法缓解多发性硬化症患者疲劳症状和负性情绪的随机对照研究,采用Cochrane手册5.1.0中的偏倚风险评估工具进行文献质量评价,采用RevMan 5.3软件进行Meta分析。结果 共纳入12项研究进行Meta分析,结果显示,正念疗法对缓解疲劳症状[SMD=-0.52,95%CI(-0.80,-0.24),Z=3.64,P<0.001]、感知压力[SMD=-1.02,95%CI(-1.48,-0.56),Z=4.35,P<0.001]、改善焦虑[SMD=-0.91,95%CI(-1.49,-0.33),Z=3.09,P<0.002]和舒缓抑郁[SMD=-0.81,51%CI(-1.30,-0.32),Z=3.25,P<0.001]有明显作用。结论 正念疗法对缓解疲劳、减轻压力、改善焦虑抑郁状况具有积极作用。 |
| 英文摘要: |
| Objective To evaluate the intervention effect of mindfulness therapy on fatigue symptoms and negative emotions in patients with multiple sclerosis. Methods CNKI, Wanfang, Weipu, China Biomedical Literature Service System, PubMed, Cochrane Library, Web of Science, EMbase, CINHL, etc.were searched sincethe establishment of database until August 12, 2021, focusing on randomized controlled study of mindfulness therapy to relieve fatigue symptomsand negative emotionsin multiple sclerosispatients, with the application of the bias risk assessment tool in the Cochrane Handbook 5.1.0 for literature quality evaluation, and RevMan 5.3 for statistical analysis. Results Twelve studies were included for Meta analysis. The results showed that mindfulness therapy could relieve fatigue symptoms[SMD=-0.52,95%CI(-0.80,-0.24),Z=3.64,P<0.001], perceive stress[SMD=-1.02,95%CI(-1.48,-0.56),Z=4.35,P<0.001], improve anxiety[SMD=-0.91,95%CI(-1.49,-0.33),Z=3.09,P<0.002]and relieve depression[SMD=-0.81,51%CI(-1.30,-0.32),Z=3.25,P<0.001]. Conclusions Mindfulness therapy has a positive effect on alleviating fatigue, reducing stress, and improving anxiety and depression. |
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