文章摘要
甲状腺良性结节微波消融治疗的临床疗效及分析
Clinical observation and analysis of microwave ablation treatment of the benign thyroid nodules
投稿时间:2023-02-14  
DOI:10.3969/j.issn.1000-0399.2023.10.007
中文关键词: 甲状腺良性结节  微波消融  体积减少率
英文关键词: Benign thyroid nodules  Microwave ablation  Volume reduction rate
基金项目:安徽省卫生健康适宜技术推广项目(编号:SYJS202123)
作者单位
申金付 236004 安徽阜阳 安徽医科大学附属阜阳市人民医院内分泌代谢科 
张学辉 236004 安徽阜阳 安徽医科大学附属阜阳市人民医院内分泌代谢科 
张琴 236004 安徽阜阳 安徽医科大学附属阜阳市人民医院内分泌代谢科 
霍琴琴 236004 安徽阜阳 安徽医科大学附属阜阳市人民医院内分泌代谢科 
韦景玉 236004 安徽阜阳 安徽医科大学附属阜阳市人民医院内分泌代谢科 
钱晓雯 236004 安徽阜阳 安徽医科大学附属阜阳市人民医院内分泌代谢科 
王静宇 236004 安徽阜阳 安徽医科大学附属阜阳市人民医院内分泌代谢科 
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中文摘要:
      目的 探讨甲状腺良性结节微波消融治疗(MWA)的临床疗效及影响因素。方法 回顾性分析2020年1月至2021年6月于安徽医科大学附属阜阳市人民医院内分泌科行MWA的68例甲状腺良性结节患者临床资料,并术后随访12月,收集并比较甲状腺结节MWA术前、术后1月、3月、6月、12月结节大小变化,及手术的不良反应等。结果 68例患者共有101枚甲状腺良性结节采用MWA术,有效率94.06%,甲状腺结节消融前、术后1月、3月、6月、12月的结节最长径、体积和体积减少率(VRR)比较,差异有统计学意义(P<0.05)。线性回归分析结果示,甲状腺结节MWA后第12月VRR的影响因素为最长径(β=-3.734,95% CI:-7.340~-0.127,P=0.043)。术后12月内严重的不良反应有:2例(2.94%)声音嘶哑,1例(1.47%)甲减。结论 MWA是甲状腺良性结节的有效治疗方法之一,结节最长径可能是甲状腺结节VRR的影响因素。
英文摘要:
      Objective To investigate the clinical efficacy and influencing factors of microwave ablation(MWA) for benign thyroid nodules. Methods A retrospective analysis was performed on 68 patients with benign thyroid nodules who underwent MWA in the Department of Endocrinology, Fuyang People's Hospital Affiliated to Anhui Medical University from January 2020 to June 2021, and were followed up for 12months after operation. The size changes of nodules and the adverse reactions of surgery were observed at 1 month, 3 months, 6 months and 12months after operation. Results A total of 101 benign thyroid nodules in 68 patients were treated with MWA, and the effective rate was 94.06%. The longest diameter, volume and volume reduction rate(VRR) of thyroid nodules before ablation, 1 month, 3 months, 6 months, and 12 months after surgery were reduced, there were statistically significant differences in the rate(P<0.05). The results of linear regression analysis showed that the influencing factor of the VRR of thyroid nodules at 12 months after MWA was the longest diameter(β=-3.734, 95% CI:-7.340~-0.127, P=0.043). In 12 months after MWA serious adverse reactions included hoarseness in 2 cases(2.94%) and hypothyroidism in 1 case(1.47%). Conclusion MWA is one of the effective treatment methods for benign thyroid nodules, and the longest diameter of nodules may be an influencing factor for the VRR of benign thyroid nodules.
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