文章摘要
UAE联合清宫术在剖宫产术后子宫瘢痕妊娠中的应用效果分析
Effect of UAE combined with curettage on uterine scar pregnancy after cesarean section
投稿时间:2022-11-14  
DOI:10.3969/j.issn.1000-0399.2023.10.010
中文关键词: 子宫动脉栓塞术  清宫术  剖宫产术后子宫瘢痕妊娠  并发症  住院时间
英文关键词: Uterine artery embolization  Uterine evacuation  Cesarean scar pregnancy  Complications  Time of hospitalization
基金项目:
作者单位
张劲杉 455000 河南安阳 安阳市第三人民医院妇产科二区 
郝俊荣 455000 河南安阳 安阳市第三人民医院妇产科二区 
张慧艳 455000 河南安阳 安阳市第三人民医院妇产科二区 
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中文摘要:
      目的 观察子宫动脉栓塞术(UAE)联合清宫术治疗剖宫产术后子宫瘢痕妊娠(CSP)患者的临床疗效。方法 回顾性分析65例2019年6月至2020年6月在安阳市第三人民医院就诊的CSP患者临床资料,按治疗方案不同进行分组,对照组行清宫术(n=32),研究组行UAE联合清宫术(n=33)。比较两组患者的治愈率、术后住院时间、临床指标、近/远期并发症、再次妊娠围产期妊娠结局。结果 研究组治愈率(100%)高于对照组(81.25%),差异有统计学意义(P<0.05),术后住院时间短于对照组,差异有统计学意义(P<0.05),月经复潮时间、血β-人绒毛膜促性腺激素(β-HCG)复常时间均早于对照组,差异有统计学意义(P<0.05),2年内正常妊娠患者人数多于对照组,差异有统计学意义(P<0.05)。两组患者不同时间点血β-HCG水平比较,组间存在差异(P<0.05),同时存在时间效应(P<0.05),不存在交互效应(P>0.05)。两组患者近、远期并发症发生率比较,差异无统计学意义(P>0.05)。结论 UAE联合清宫术可提高CSP患者的治愈率、再次正常妊娠率,促进月经复潮、血β-HCG复常,缩短患者的术后住院时间,且未增加近/远期并发症。
英文摘要:
      Objective To observe the clinical efficacy of uterine artery embolization(UAE) combined with curettage in the treatment of cesarean scar pregnancy(CSP). Methods The clinical data of 65 CSP patients treated in Anyang Third People's Hospital from June 2019 to June 2020 were collected and retrospectively analyzed. The control group(n=32) all underwent uterine evacuation, and the study group(n=33) all underwent UAE combined with uterine evacuation. The cure rate, postoperative hospital stay, clinical indicators, short-term/long-term complications, and perinatal pregnancy outcomes of re-pregnancy were compared between the two groups. Results The cure rate of the study group(100%) was higher than that of the control group(81.25%), and the difference was statistically significant(P<0.05); the postoperative hospital stay was shorter than that of the control group, and the difference was statistically significant(P<0.05); the time of menstrual rehydration and the blood beta-human chorionic gonadotropin(β-HCG) normalization time were earlier than those of the control group, and the difference was statistically significant(P<0.05); the number of patients with normal pregnancy in the study group was larger than that in the control group within two years, and the difference was statistically significant(P<0.05). The variance analysis of the repeated measurement of β-HCG at different time points of the two groups showed difference, and there were intergroup differences(P<0.05), concurrent time effect(P<0.05) but no interaction effect(P> 0.05). There was no obvious difference in the incidence of short-term and long-term complications between the two groups(P>0.05). Conclusions UAE combined with uterine evacuation can improve the cure rate of CSP and the rate of normal pregnancy again, promote the return of menstruation and normalization of blood β-HCG, and shorten the postoperative hospital stay of patients without increasing short-term or long-term complications.
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