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| 2023版Beers标准联合STOPP/START标准对心内科老年患者潜在不适当用药评价分析 |
| Analysis of potentially inappropriate medication in elderly cardiology patients based on Beers （2023 edition） and STOPP/START criteria |
| 投稿时间：2024-07-05 |
| DOI：10.3969/j.issn.1000-0399.2025.05.003 |
| 中文关键词: 老年患者|心内科|潜在不适当用药|Beers标准|STOPP/START标准 |
| 英文关键词: Elderly patients|Cardiology department|Potentially inappropriate medication|Beers criteria|STOPP/START criteria |
| 基金项目:安徽省自然科学基金项目(编号:2108085MH257); 联勤保障部队第901医院科研项目(编号:2023YGYB12) |
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| 中文摘要: |
| 目的 分析心内科老年患者潜在不适当用药（PIM）情况，为临床药师PIM干预提供依据，为临床医师提供更精准的合理用药指导。方法 回顾性分析中国人民解放军联勤保障部队第901医院心内科2022年1～7月收治的261例年龄≥65岁老年患者的住院病历资料，采用最新版Beers标准（2023版）、STOPP/START标准（2014版）对入组老年患者潜在用药风险进行评价，分析心内科老年患者的用药现状及PIM发生情况，并采用logistic回归分析法探究PIM的影响因素。结果 根据Beers标准，审查出184例患者发生PIM 283次；根据STOPP标准，审查出57例患者发生PIM 69次；根据START标准，审查出90例患者存在122次用药遗漏的PIM情况。logistic回归分析表明，Beers标准提示年龄大、住院时间长、用药种类数多是PIM的危险因素（P<0.05);STOPP/START标准提示年龄大、住院时间长是PIM的危险因素（P<0.05） 。结论 心内科老年住院患者的PIM发生率较高，使用2种评估标准可全面地筛查出老年患者的PIM，能有效降低药物不良事件的发生，提高老年患者合理用药水平。 |
| 英文摘要: |
| Objective To analyze the situation of potentially inappropriate medication（PIM） in elderly cardiology patients so as to provide basis for clinical pharmacists intervention in PIM and more accurate guidance for rational drug use for clinicians. Methods The inpatient medical records of ≥65 years old older patients in the Cardiology Department of the 901 Hospital of Joint logistic Support Force from January to July 2022 were retrospectively analyzed, and the potential risks of medication in 261 older patients enrolled in the study were evaluated and analyzed by using the latest version of the Beers（2023） and STOPP/START criteria（2014） to understand the current status of medication in elderly cardiology patients and the incidence of PIM, and a logistic regression analysis was used to explore the influencing factors of PIM. Results PIM occurred 283 times in 184 patients reviewed according to the Beers criteria, 69 times in 57 patients reviewed according to the STOPP criteria, and 122 medication omissions in 90 patients reviewed according to the START criteria. Logistic regression analysis showed that older age, longer hospitalization and more drug types were the risk factors for PIM（P ＜ 0.05）. Age and long hospital stay were the risk factors for PIM by STOPP/START criteria（P ＜ 0.05）. Conclusion The incidence of PIM in elderly cardiology patients is high.The use of two evaluation criteria can comprehensively screen PIM in olderly patients, which can effectively reduce the occurrence of adverse drug events and improve the level of rational drug use in elderly patients. |
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