| Objective To evaluate the predictive value of the electrocardiographic Tp-e/QT ratio for short-term clinical outcomes in acute intracerebral hemorrhage(ICH) patients. Methods We conducted a retrospective analysis of 127 patients diagnosed with ICH who received treatment at the Second Affiliated Hospital of Anhui Medical University from May 2021 to June 2024. Based on the Glasgow Outcome Scale(GOS) at discharge, patients were categorized into two groups: poor prognosis group(n=61, GOS score 1～3) and good prognosis group(n=66, GOS score 4～5). Clinical data and electrocardiogram(ECG) parameters were compared between groups. We employed multivariate logistic regression to pinpoint independent prognostic factors associated with unfavorable short-term outcome. The predictive performance of the Tp-e/QT ratio was assessed using receiver operating characteristic(ROC) curves. Results Compared with the good prognosis group, the poor prognosis group had higher rates of surgical intervention and intraventricular hemorrhage, along with significantly elevated white blood cell count, neutrophil count, National Institutes of Health Stroke Scale(NIHSS) score at admission, heart rate, Tp-e interval, Tp-e/QT ratio, and corrected QT interval(QTc). In contrast, the admission Glasgow Coma Scale(GCS) score and RR interval were significantly lower(P<0.05). Multivariate logistic regression revealed that intraventricular hemorrhage, Tp-e/QT ratio, and NIHSS score at admission were independent risk factors for poor short-term prognosis(P<0.05). ROC analysis demonstrated that the Tp-e/QT ratio had a significantly greater area under the curve(AUC) than QTc in predicting poor outcomes(P<0.001). Conclusion An elevated Tp-e/QT ratio is closely associated with poor short-term prognosis in ICH patients. It demonstrates strong predictive value and has the potential to serve as a non-invasive biomarker for early risk stratification in this patient population. |
