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| 基于解剖结构的胎儿MRI场强选择策略：1.5 T与3.0 T成像效能对比研究 |
| Fetal MRI field strength selection strategy based on anatomical structures: a comparative study of imaging efficacy between 1.5T and 3.0T |
| 投稿时间：2025-06-25 |
| DOI：10.3969/j.issn.1000-0399.2026.02.003 |
| 中文关键词: 磁共振成像 产前诊断 图像质量 胎儿 效果评价 |
| 英文关键词: MRI Prenatal diagnosis Image quality Fetus Outcome evaluation |
| 基金项目:中国疾病控制中心妇幼保健中心母婴营养与健康研究(编号:2022FYH007) |
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| 中文摘要: |
| 目的 探讨不同孕周与场强MRI对胎儿多部位解剖结构的成像差异，建立基于解剖特征的场强选择策略。方法 回顾性分析2022-2025年安徽省儿童医院行MRI检查的100例胎儿临床资料，按1.5 T和3.0 T场强分组，各50例。采用Likert 5分量表由2名高年资医师对两组胎儿颅脑、脊柱脊髓、心脏大血管及腹部4个部位的成像质量进行盲法独立评分。采用加权Kappa检验评估评分者间一致性。应用Mann-Whitney U检验比较组间图像质量评分的差异，为控制孕周潜在混杂影响，进一步按孕周（<25周、25～32周、>32周）分层进行亚组分析。结果 3.0 T组在脊柱脊髓成像中的秩和值优于1.5 T组（Z=-4.973,P<0.001）；亚组分析显示，3.0 T在25～32周的胎儿中优势最明显（P<0.001）。1.5 T组在心脏大血管成像中表现更佳（Z=-5.759,P<0.001）；亚组分析显示，1.5 T在25～32周的胎儿中优势明显（P<0.001）。1.5 T和3.0 T组间颅脑（Z=-0.272,P=0.786）及腹部（Z=-1.618,P=0.106）成像质量差异无统计学意义（P>0.05），不同孕周亚组间胎儿腹部和颅脑成像质量差异无统计学意义（P>0.05）。结论 胎儿MRI成像质量与场强存在解剖依赖性特征，建议脊柱脊髓成像优选3.0 T场强，心脏大血管检查采用1.5 T场强，对于颅脑及腹部成像，1.5 T与3.0 T场强具有同等的适用性，可根据临床实际情况灵活选择。 |
| 英文摘要: |
| Objective To explore the imaging differences in multiple fetal anatomical structures between different gestational ages and field strengths of MRI, and to establish a field strength selection strategy based on anatomical features. Methods A retrospective analysis was performed on clinical data from 100 fetuses who underwent MRI examinations at Anhui Children's Hospital between 2022 and 2025. The subjects were divided into two groups based on magnetic field strength: a 1.5 T group and a 3.0 T group, with 50 cases in each. Two senior radiologists independently and blindly assessed the image quality of four anatomical regions(brain, spinal cord, cardiovascular, and abdomen) in both groups using a Likert 5-point scale. Interobserver agreement was evaluated with the weighted Kappa test. Differences in image quality scores between groups were compared using the Mann-Whitney U test. To control for the potential confounding effect of gestational age, subgroup analysis was further conducted by stratifying gestational age into three categories: <25 weeks, 25～32 weeks, and >32 weeks. Results Field strength demonstrated anatomical region-dependent effects on image quality. Specifically, for fetal spinal cord imaging, the 3.0T group showed significantly better image quality scores than the 1.5 T group(Z=-4.973, P < 0.001), with the most notable advantage observed in the 25～32 gestational weeks subgroup(P < 0.001). In contrast, for cardiovascular imaging, the 1.5 T group outperformed the 3.0 T group(Z=-5.759, P < 0.001), and this advantage was also most evident in the 25～32 gestational weeks subgroup(P < 0.001). No statistically significant differences were found between the two field strengths in fetal brain(Z=-0.272, P= 0.786) or abdominal imaging(Z=-1.618, P= 0.106). Additionally, gestational age did not significantly affect image quality in these two anatomical regions across subgroups(P> 0.05). Conclusion The quality of fetal MRI exhibits an anatomical dependency on magnetic field strength. It is recommended to prioritize 3.0 T for spinal cord imaging and 1.5T for cardiovascular evaluation. For imaging of the brain and abdomen, both 1.5 T and 3.0 T demonstrate comparable applicability and can be selected based on specific clinical circumstances. |
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