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| 健康促进行为在宫颈癌术后患者恐惧疾病进展和生活质量间的中介效应分析 |
| Analysis of the mediating effect of health-promoting behaviors between fear of disease progression and quality of life in postoperative cervical cancer patients |
| 投稿时间：2025-04-23 |
| DOI：10.3969/j.issn.1000-0399.2026.02.017 |
| 中文关键词: 宫颈癌 恐惧疾病进展 健康促进行为 生活质量 中介效应 |
| 英文关键词: Cervical cancer Fear of disease progression Health-promoting behaviors Quality of life Mediating effect |
| 基金项目:四川省卫生健康委员会科技项目(编号:2022JDXM006); 超声医学工程国家重点实验室开放课题面上项目(编号:2023KFKT014) |
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| 中文摘要: |
| 目的 探讨健康促进行为在宫颈癌术后患者恐惧疾病进展与生活质量间的中介作用，旨在改善患者生活质量，为制定有效的干预措施提供依据。方法 采用便利抽样法，选取2025年1月～3月四川省南充市两所三级甲等医院收治的宫颈癌术后237例患者作为调查对象。采用自行设计的一般资料调查表、癌症患者恐惧疾病进展简化量表（FoP-Q-SF）、健康促进生活方式量表（HPLP-ⅡR）、宫颈癌生活质量评价量表（FACT-G）对纳入的研究对象进行调查，采用Pearson相关分析探讨恐惧疾病进展、健康促进行为、生活质量之间的相关性。采用PROCESS4.1插件中的模型4检验中介效应。结果 共回收问卷243份，其中有效问卷237份，有效问卷回收率为97.53%。宫颈癌术后患者FoP-Q-SF总分、HPLP-ⅡR总分、FACT-Cx总分分别为（32.22±5.97）分、（97.12±10.30）分、（107.65±15.45）分。FoP-Q-SF与HPLP-ⅡR、FACT-Cx得分均呈负相关（r=-0.247,P<0.001）、（r=-0.556,P<0.001）;HPLP-ⅡR与FACT-Cx呈正相关（r=0.511,P<0.001）；健康促进行为在恐惧疾病进展对生活质量的影响中存在部分中介效应（β=-0.138,P<0.001），中介效应占比9.70%。结论 恐惧疾病进展可以直接影响患者的生活质量，也可以通过健康促进行为间接影响生活质量。护理人员可采取有效的措施来降低患者恐惧疾病进展的心理，树立良好的健康行为进而提升患者的生活质量。 |
| 英文摘要: |
| Objective To explore the mediating role of health-promoting behaviors between fear of disease progression and quality of life in postoperative cervical cancer patients, aiming to improve patients' quality of life and provide a basis for developing effective interventions. Methods Using convenience sampling, cervical cancer patients admitted to two tertiary hospitals in Nanchong from January 2025 to March 2025 were selected as the survey subjects, and all patients underwent surgical treatment. The survey was conducted using the General Information Questionnaire, the Fear of Progression Questionnaire-Short Form(FoP-Q-SF), the Health-Promoting Lifestyle Profile-II Revised(HPLP-ⅡR), and the Functional Assessment of Cancer Therapy-Cervix(FACT-Cx). Results A total of 243 questionnaires were collected, with 237 valid responses, yielding an effective response rate of 97.53%. The total score of FoP-Q-SF, HPLP-ⅡR, and FACT-Cx for postoperative cervical cancer patients was(32.22 ± 5.97),(97.12 ± 10.30), and(107.65 ± 15.45), respectively. FoP-Q-SF was negatively correlated with HPLP-ⅡR(r=-0.247, P < 0.001) and FACT-Cx(r=-0.556, P < 0.001), while HPLP-ⅡR was positively correlated with FACT-Cx(r= 0.511, P< 0.001). Health-promoting behaviors partially mediated the effect of fear of disease progression on quality of life(β=-0.138, P< 0.001), accounting for 9.70% of the total effect. Conclusion Fear of disease progression can directly affect quality of life and indirectly influence it through health-promoting behaviors. Nursing staff can take effective measures to reduce patients' fear of disease progression, establish healthy behaviors, and thereby improve their quality of life. |
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