| Objective To compare the clinical efficacy and safety of laparoendoscopic single-site surgery and conventional laparoscopic surgery in the treatment of ovarian cysts. Methods The clinical data of 86 patients with ovarian cysts who underwent surgical treatment at Wuhan First Hospital from February 2023 to March 2024 were retrospectively analyzed. According to the surgical approach, they were divided into a LESS group and a CLS group, with 43 cases in each group. The baseline characteristics of the two groups were compared, including age, body mass index(BMI), cyst diameter, preoperative CA125 level, and marital/childbearing status. The differences between the two groups in intraoperative blood loss, postoperative time to first flatus, hospital stay duration, pain scores at 24 h and 48 h postoperatively, and the incidence of postoperative complications were compared. Furthermore, changes in ovarian function indicators were compared between the two groups, including levels of luteinizing hormone(LH), follicle-stimulating hormone(FSH), and estradiol(E2). Additionally, subgroup analysis was performed based on age(≤35 years vs. >35 years), with a focus on comparing the differences in changes in anti-Müllerian hormone(AMH). Results There was no statistical difference in baseline data between the two groups(P>0.05). The LESS group was superior to the CLS group in terms of intraoperative blood loss(P=0.035), postoperative exhaust time(P<0.001), hospital stay(P<0.001), and pain scores at 24 h and 48 h postoperatively(P<0.001). Analysis of ovarian function showed no significant differences in the changes of LH, FSH, and E2 beP tween the two groups(all >0.05); however, in patients aged ≤35 years, the decline in Anti-Müllerian Hormone(AMH) was significantly smaller in the LESS group than in the CLS group(P=0.028). There was no statistically significant difference in the total incidence of postoperative complications between the two groups(P=0.314). Conclusion Compared with conventional laparoscopic surgery, LESS has advantages in reducing intraoperative trauma, accelerating postoperative recovery, alleviating pain, and better protecting ovarian function in the treatment of ovarian cysts, with good safety and high clinical application value. |
