| Objective To analyze the correlation between the anatomical characteristics of patent foramen ovale(PFO) and cryptogenic stroke, and to guide clinical treatment. Methods A retrospective analysis was conducted on the data of 438 patients with PFO diagnosed in the Department of Cardiovascular Surgery of the First Affiliated Hospital of Anhui Medical University from June 2018 to December 2024. All patients were diagnosed with cryptogenic stroke by head CT and/or MRI. All patients underwent ultrasound-guided percutaneous PFO closure under general anesthesia. According to the size of the foramen ovale, they were divided into the small PFO(n=304) and medium to large PFO(n=134). According to the presence or absence of right-to-left shunt at rest, they were divided into the no shunt(n=349) and shunt group(n=89). According to the right heart contrast echocardiography grade, they were divided into the grade Ⅱ(n=74) and grade Ⅲ group(n=364). According to the type of PFO, they were divided into the common type(n=318) and complex type group(n=120). The differences in the incidence of cryptogenic stroke among the groups were compared, and the relationship between the anatomical factors of PFO and cryptogenic stroke was explored. Results After excluding the differences in age and body weight, the incidence of cryptogenic stroke was significantly different among patients with small and medium to large PFO, those with or without shunt at rest, those with grade Ⅱ and grade Ⅲ right heart contrast echocardiography, and those with common and complex types of PFO(P<0.05). Conclusion Patients with medium to large PFO, right-to-left shunt at rest, grade Ⅲ right heart contrast echocardiography, and complex type PFO have a higher incidence of cryptogenic stroke, thus intervention and treatment should be carried out earlier. |
