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| 重复经颅磁刺激治疗对脑卒中患者认知功能的影响及与情感淡漠的相关性分析 |
| The impact of repetitive transcranial magnetic stimulation therapy on cognitive function and its correlation with emotional therapy in stroke patients |
| 投稿时间：2025-07-28 |
| DOI：10.3969/j.issn.1000-0399.2026.05.011 |
| 中文关键词: 脑卒中 重复经颅磁刺激 认知功能 情感淡漠 相关性 |
| 英文关键词: Stroke Repetitive transcranial magnetic stimulation Cognitive function Emotional apathy Correlation |
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| 中文摘要: |
| 目的 分析重复经颅磁刺激治疗（rTMS）对脑卒中患者认知功能的影响及与情感淡漠的关系。方法 回顾性分析2023年3月至2024年5月阜阳市中医医院康复中心100例脑卒中幸存患者资料，按治疗方式不同分为研究组（rTMS）和对照组（常规治疗），各组50例。比较治疗前、治疗后第4周及治疗后第8周两组患者的认知功能[蒙特利尔认知量表（MoCA）]和情感淡漠水平[冷漠评估量表（AES-C）]差异；以治疗8周后MoCA评分≥26分为界，将患者分为认知障碍组（67例）和认知正常组（33例），单因素、多因素logistic回归分析脑卒中患者认知功能的影响因素；使用Pearson相关性分析脑卒中患者认知功能与情感淡漠的相关性。结果 治疗4周、8周后，两组患者MoCA得分均升高，AES-C得分均降低，研究组得分优于同期对照组（P<0.05），且重复测量方差分析结果显示，两组MoCA、AES-C得分组间、时间及交互效应差异均有统计学意义（P<0.05）。Logistic回归模型分析结果显示，年龄大、高血压、糖尿病、教育水平低、情感淡漠得分高是认知功能障碍的影响因素（P<0.05）;Pearson相关分析结果显示，脑卒中患者情感淡漠程度与认知功能障碍呈正相关（P<0.05）。结论 rTMS可改善脑卒中患者的认知功能和情感淡漠症状，脑卒中患者认知功能与年龄、教育水平、基础疾病史及情感淡漠水平密切相关，情感淡漠程度越高，认知功能越差。 |
| 英文摘要: |
| Objective To analyze the effect of repetitive transcranial magnetic stimulation(rTMS) on the cognitive function of stroke patients and its relationship with emotional apathy. Methods The clinical data of 100 stroke survivors admitted to the Rehabilitation Center of Fuyang Hospital of Traditional Chinese Medicine from March 2023 to May 2024 were retrospectively analyzed. The patients were divided into the study group(rTMS treatment) with 50 cases and the control group(conventional treatment) with 50 cases based on different treatment methods. The differences in cognitive function [Montreal Cognitive Assessment(MoCA)] and emotional apathy level [Apathy Evaluation Scale(AES-C)] between the two groups before treatment and 4 weeks, 8 weeks after treatment were compared; patients were divided into the cognitive impairment group(67 cases) and the cognitive normal group(33 cases) based on a MoCA score ≥ 26 after eight weeks of treatment. Univariate and multivariate logistic regression analyses were used to analyze the influencing factors of cognitive function in stroke patients; Pearson correlation analysis was used to analyze the correlation between cognitive function and emotional apathy in stroke patients. Results After 4 weeks and eight weeks of treatment, the MoCA scores of both groups increased, and the AES-C scores decreased. The scores of the study group were higher than those of the control group at the same time(P<0.05). The results of the repeated measures analysis of variance showed that there were statistically significant differences in the scores of MoCA and AES-C between the two groups, as well as in time and their interaction effects(P<0.05). Logistic regression model analysis showed that age, hypertension, diabetes, low education level, and high apathy score were the influencing factors of cognitive dysfunction(P<0.05); Pearson correlation analysis results showed that the score of emotional apathy in stroke patients was significantly positively correlated with cognitive dysfunction(P<0.05). Conclusion rTMS can significantly improve the cognitive function and emotional apathy symptoms of stroke patients. The cognitive function of stroke patients is closely related to age, education level, underlying disease history, and emotional apathy level. The higher the level of emotional apathy, the worse the cognitive function. |
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