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| 一起社区诺如病毒感染疫情调查及病毒基因型分析 |
| Investigation and genotype analysis of norovirus infection in a community |
| 投稿时间：2021-09-22 |
| DOI：10.3969/j.issn.1000-0399.2022.04.021 |
| 中文关键词: 诺如病毒 传播危险因素 聚集性疫情 |
| 英文关键词: Norovirus Risk factors of transmission Aggregation epidemic |
| 基金项目:安徽省卫生计生委科研计划项目（项目编号:2017jk003） |
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| 中文摘要: |
| 目的 调查某社区一起感染性腹泻疫情原因，分析病原基因型，为防控感染性腹泻疫情提供科学依据。方法 2020年11月，采取病例定义、病例搜索、个案流行病学调查、病例对照研究、采集肛拭子检测等方法，对合肥市X小区感染性腹泻疫情开展调查，并利用分子生物学与生物信息学技术分析病原基因型。结果 该起事件共报告13例患者，罹患率为0.14%（13/9 102）；样本检测结果显示为诺如病毒，基因进化分析为诺如病毒GⅡ.4[P31]型。结论 本起事件为诺如病毒引起的感染性腹泻疫情，最可能的传播途径为社区外环境接触传染，源头可能是由社区外传入。 |
| 英文摘要: |
| Objective To investigate the cause of an epidemic of infectious diarrhea in a community and analyze the pathogen genotypes, providing scientific basis for the prevention and control of epidemic of infectious diarrhea. Methods A infectious diarrhea broke out in community X in Hefei in November 2020.The case was investigated by means of case definition, case search, epidemiological investigation, case-control research and anal swab detection, and the pathogen genotypes were analyzed by molecular biology and bioinformatics techniques. Results A total of 13 patients were reported in this case, with a morbidity rate of 0.14% (13/9 102).The results showed that the samples were norovirus, and the genetic evolution analysis was norovirus GII.4[P31].Conclusion This incident is an outbreak of infectious diarrhea caused by norovirus. The most likely route of transmissionis outside the community, and the source may have been introduced from outside the community. |
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